4 Troubled Teens Blog

Study Questions Genetic Basis of Depression

An influential 26-year study of 847 individuals that ended in 2003 found that if people had a certain gene, they were more likely to become depressed after a traumatic life event such as bankruptcy or death of a loved one.

The same study found that if people had a different gene variant, they were more likely to go through such events without experiencing major depression. This study was widely accepted and became the basis of a belief that depression is an organic disorder that can be treated through medication.

Now a new study reports having found "no evidence of an association between the serotonin gene and depression," even if a person experiences a traumatic event. The new study, led by Dr. Neil Risch and Dr. Kathleen Merikangas, is an analysis of 14 previous studies.

In their report in the Journal of the American Medical Association, Drs. Risch and Merikangas indicated that they believe that the old study had flaws. They also wrote that the old study was widely accepted before it was widely duplicated.

Labels: depression, research, genetics

Posted By: Aspen/CRC